The Human Genome, Gene Therapy, and the Irrelevancy of God

Roots. We all have them, embedded somewhere in our past. I don’t recall my birth father and have never visited his grave in Biloxi, Mississippi. My parents were married in 1932, when he was 41 and she 27. I was born in 1934, and he died in 1939. I never had a chance to observe him for the ways in which I might be a chip off his old block. Nevertheless, a good part of who I have become has been determined by who he was and his contribution to my inherited gene pool.

Who we are physically is heavily rooted in the combined gene pool of our parents. Such features of ourselves as the color of our eyes, hair, and skin, our height and gender, and our susceptibility to various diseases are all an outgrowth of our parental gene pool. Your inherited genes can even influence such things as mental abilities, personality traits, and predisposition to certain kinds of talents and abilities. If a person, upon looking in a mirror one morning, is pondering the image that stares back, s/he might check out some old family photos. On the other hand, s/he might consider gene therapy. As incredible as it may sound, gene therapy can involve replacing a defective gene in your present genetic code, silencing a faulty gene, or editing specific DNA sequences.¹

Depending on your politics and/or religious persuasion, gene therapy may sound like science fiction to the unpracticed ear but, like it or not, gene therapy has quietly moved into real life. Messing about in the human genome may evoke images of Dr. Mengele² or Victor Frankenstein (a character in Mary Shelley’s 1818 fiction novel Frankenstein), but if such treatment can improve the human situation, why not?

If you are religious in a traditional sense (an avid church/synagogue/mosque attender), gene therapy may also suggest that those involved in genome research are playing God. At bottom, such an accusation “refers to the powers that science, engineering, and technology confer on human beings to understand and to control the natural world, including you.”³ In aiming at the ability to create life in a petri dish such researchers encroach on a role that has traditionally belonged to God (Gen 1:1-31, for example). And in fact, they have successfully created a kind of artificial life, the first synthetic cell: “it is the first self-replicating cell on the planet [whose] parent is a computer.”⁴

If (or when) they succeed in discovering how to create life de novo, however, they will not have proven the non-existence of God but rather threatened the relevancy of the concept of God. If human beings can create life, even artificial life, and change the human genome so as to alter what God is believed to have accomplished through Mother Nature, God becomes something like a good luck charm to which many may turn in times of crisis—when the limits of human knowledge and ability are reached.

All of what I have just described evokes aspects of the biblical Tower of Babel story (Gen 11:1-9). The sons of men built a city and a tower “with its top in the heavens.” And Yahweh, upon coming down to see the city and the tower, said: “this is only the beginning of what they will do; and nothing they propose to do will now be impossible for them” (Gen 11:5 RSV). The story portrays Yahweh and his court (“Let us go down and confuse their language so they may not understand one another’s speech,” Gen 11:7 RSV) being intimidated by human accomplishments. Hence, God destroyed their ability to communicate and scattered them around the world (Gen 11:8-9). Apparently, Yahweh sensed that given their present course the sons of men would render the divine Self irrelevant.

Losing relevancy is a genuine, practical, existential threat to a God. Just consider how many Gods through history have fallen into irrelevancy and, eventually, into oblivion. Irrelevant Gods wait, one assumes, in a kind of mythical Nirvana to be rediscovered, to wait until someone calls upon them again and thereby renders them relevant. Or does irrelevancy mean actual death for a God? Has anyone out there ever heard of an irrelevant God being restored to relevancy to “run” the world again?

Charles W. Hedrick
Professor Emeritus
Missouri State University

¹fda.gov/vaccines-blood-biologics/cellular-gene-therapy-products/what-gene-therapy

And: en-wikipedia.org/wiki/Gene-therapy

²en.wikipedia.org/wiki/Josef_Mengele

³https://www.encyclopedia.com/science/encyclopedias-almanacs-transcripts-and-maps/playing-god

⁴newscientist.com/article/dn18942-immaculate-creation-birth-of-the-first-synthetic-cell/

Losing your Soul

Several years before I retired from Missouri State University in 2005, I was so caught up in an active academic career, involved in campus life, community activities, professional activities, and serving in the Army Reserve that I felt like my very soul was at risk. Somewhere between completing a terminal degree (1977) and retiring from Missouri State University (2005), my soul seemed to have gone missing or was so shriveled I could not find it. Souls need attention, special feeding and watering, to flourish. I suspect that I am not the only person to come to this realization.

            You might not think it possible for people to lose their souls, but Jesus thought so. “What is the profit,” he said, “in gaining the world and losing your soul” (Mark 8:36). Charles Dickens also thought so, and in his novel (A Christmas Carol) portrayed Ebenezer Scrooge as a soulless man, who rediscovers his soul at the end of the novel. “Soul” is the essence of being truly human—a quality always pushing us, come hell or high water, toward moral excellence. A man or a woman with no soul has lost the qualitative edge of being human, of keeping life in balance and everything in perspective—in other words, “losing yourself to gain the world” (Luke 9:25) distorts perspective and throws life into serious imbalance. Clearly Scrooge was disoriented. He had fed his soul so much material “stuff” that he had lost touch with humanity—particularly his humanity. In my case, somewhat like Bob Cratchit, I sat in a tiny windowless office cluttered with neglected professional projects (real soul food by the way), and fed my soul unimaginative papers by incurious students, but in the grand scheme of things virtually irrelevant. Souls cannot survive on such an unbalanced diet.

            Can governments lose their souls? Certainly, they can. Government at every level involves people who set a tone for the administration and carry out its policies. National socialism in Hitler’s Germany, at best, was government without conscience or humanity, and its systematic massacre of Jews and other eastern Europeans clearly qualifies it as soulless. The same is true of Saddam Hussein’s Iraqi government, for attempting to annihilate its own citizens, the Kurds. In our own country, the suppressive disfranchisement (and worse!) of black citizens in the deep south for over one hundred years can only be explained by the shriveled souls of white citizens. And what should we say about attempts in various states to eliminate budgetary support for our most vulnerable citizens—the mentally ill, disabled, children, and the elderly? At best, it is not an action that anyone would confuse with moral excellence. And Mr. Trump’s “One Big Beautiful Bill Act” by congress? The Congressional Budget Office estimates that its passage may cause some 10 million American citizens to lose their health insurance by 2034, with some $900 billion in cuts to Medicare. Only shriveled souls could be pleased at such an inhumane result.¹

            Can a church lose its soul? You wouldn’t think so, but in my religious tradition it has been happening for some time now. For the sake of what some in the tradition regard as “right” theology, Southern Baptist intolerants dismantled a fellowship of, more or less, independent cooperating churches. They centralized their authority and have been, since 1985, purging the denomination of diversity. Shortening the borders of the tent and shallow thinking make for better control but do not encourage the development of healthy souls.

Without a healthy soul, we will never find our way to the moral high road, or as Paul put it, to the more excellent way (1 Cor 12:3–13:13). Without soul one is condemned to sit among the mattresses of the dead (a line from a poem by Wallace Stevens, The Man on the Dump). Allowing a soul to shrivel away is bad enough. Being unaware of the loss altogether is a crisis of epic proportions!²

Charles W. Hedrick
Professor Emeritus
Missouri State University

¹https://www.cbpp.org/research/health/by-the-numbers-republican-reconciliation-law-will-take-health-coverage-away-from#:~:text=as%20their%20employment.-,Medicaid,had%20an%20illness%20or%20disability

²This essay, reedited and updated in part, was first published in the newspaper, the Springfield News Leader, Springfield, MO, before 2009, and republished in my book, House of Faith or Enchanted Forest? American Popular Belief in an Age of Reason (Cascade, 2009), 34-35.